Synthesis and spectroscopic analysis of the structure and oxidizing ability of Fe3O4 magnetic fluid nanoparticles.

Abstract

Synthesis and spectroscopic analysis of the structure and oxidizing ability of Fe3O4 magnetic fluid nanoparticles.

Kochkina V.K. Polozhentsev O.E. Mazalova V.L.

Incoming article date: 20.10.2014

In this paper we investigated the structure of the magnetic fluid based on Fe3O4 nanoparticles. Magnetic fluid based on Fe3O4 nanoparticles is used for cancer treatment, targeted drug delivery, hyperthermia, as a contrast agent in surgery, as a barrier to blood flow and others. Magnetic fluid based on Fe3O4 nanoparticles was synthesized by chemical condensation of magnetite nanoparticles. Characteristics of magnetic fluid (oxidation of iron nanoparticles size, density) were investigated using X-ray absorption spectroscopy. The changes of the antitumor effect of the magnetic fluid is associated with an increase of the particle size of the iron oxide that has a significant impact on their penetration in a tumor tissue.

Keywords: magnetic fluid, magnetite, nanoparticles, Fe3O4, oxidation state, density, antitumor activity