The description of the developed software to apply digital video-ocular DCM-310 in the process of the histological examination is provided. The program allows us to display on the computer screen tissue samples and automatically measure the region of interest. This allows the doctor-pathologist to perform work at a high technical level and increase the efficiency of his work.

Keywords: histology, diagnostics of malignant tumours, biopsy, measurements, video-ocular, software, microscope

The article presents the position of Russia in the global energy sector, highlighted the global trends of the modern development of economic systems that directly affect the stability of the national industrial complexes. Presented the need to invest investments in Russian regional power generation systems.

Keywords: Trading network, supply chain, suppliers, government regulation, institutionalization of exchange relations.

To assess the genotoxicity of environmental urban ecosystems appropriate to use indicators geno-and cytotoxic extract pilezii Multiflora. Geno-and cytotoxicity of the extract can be assessed by the level of chromosomal aberrations, as well as indicators of the mitotic index in the root meristem of pea, germinated on an extract pilezii Multiflora. When using indicators geno-and cytotoxicity in urban ecosystems should talk about the genotoxicity of the environment in the case of a statistically significant difference from the control of these parameters.

Keywords: biomonitoring, mutagenicity, test object, chromosome aberrations, cytotoxicity, genotoxicity

Alzheimer's disease is an incurable illness. It affects about half a million people in Russia, and due to the general trend towards aging of the population the number of Alzheimer's disease cases will steadily increase. Insoluble deposits of amyloid beta in the brain tissue (amyloid plaques) are the major morphological characteristic of Alzheimer's disease. It has been found that the increased concentration of copper in amyloid plaques results in copper ions bound to the protein. It is the presence of copper in the binding site triggers of the formation of amyloid plaques. Therefore, the study of the binding site in amyloid beta is of great scientific interest. The local atomic structure of the Cu(I) copper ion binding site in the amyloid beta peptide has been studied by means of XANES spectroscopy. Several model structures obtained by molecular mechanics and density functional theory (ADF code) have been tested. Theoretical analysis of X-ray absorption spectra based on the finite difference method implemented in FDMNES code was performed. An appropriate model structure of the Cu(I) copper ion binding site in amyloid beta peptide has been found.

Keywords: amyloid beta, binding site, Alzheimer's disease, the method of finite differences, Cu(I)

The problems of mm propagation: rain attenuation,  depolarization and gaseous absorption are considered, and the estimate of the energy potential of wireless mobile data transport networks is given. The dependence on the output power of the distance and the total losses, and the necessary signal levels for different types of modulation being shown.  The estimate of the interfering transmitters effect of side lobes of the antenna is given.  

Keywords: radio wave propagation, mm range, energy potential, rain clutter, side lobes, polar pattern

  The work is devoted to the development of an intelligent system for monitoring high railway embankment, which allows to analyze its condition and make early solutions to manage the safety of vehicles. The main features of the system and its difference from known analogs is taking into account the dynamic effects of vehicles on a high embankment at different climatic conditions. This paper describes the main stages of building the monitoring system, which includes: selection of objects for monitoring, computer modeling of the interaction of the rolling stock and a high embankment, the algorithms required for the development of management decisions. 

Keywords: high embankments, risk assessment, destruction, monitoring, computer modeling, intelligent system.

The article deals with the social responsibility of business, provides a definition and direction of social policy, and discusses its objects and subjects. In a brief review of points of view stand four types of regions according to the degree of social influence business. It is suggested that the social responsibility of business is a factor of regional social policy and provides a list of the positions of social responsibility, as well as nine motifs stimulate business to social activities in the region.

Keywords: social responsibility of business, entrepreneurship, region.

Information about authors of issue №2 (2012)

Keywords: authors

Information about authors of issue №4 (2011)

Keywords: authors

Keywords: innovation development, Skolkovo, formation of needs in innovation, expertise and administrative core, the new grant program, expert advice, the Polytechnic Museum, breakthrough design, nanotechnology, new wastewater treatment technology, high temperature superconductivity.

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